| history |
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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-25 04:29:46'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1767344516', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-24 05:06:11'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-23 04:00:29'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-23 04:00:28'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-22 04:57:51'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-21 01:07:25'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-20 01:05:24'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 79.0, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 106.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-19 01:07:49'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-18 01:07:58'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-17 19:01:45'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-17 09:11:52'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1767344516', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-17 05:34:32'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1767344516', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-17 01:07:34'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-16 21:44:33'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'partial_update': 0, 'product_images': []}, 'date': '2026-07-16 16:01:33'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1767344516', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; Size: BUNDLE(2000+7500)', 'remote_code': '41200136585264', 'stock_count': 1, 'origin_color': 'Default', 'variant_images': ['https://cdn.shopify.com/s/files/1/0156/3905/2336/files/03_d7a3e2a5-83aa-4121-b66b-62fe9d2c5c03.jpg?v=1767344516', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/123_b949163c-ce8e-493e-8df8-6187dd286917.jpg?v=1760666386', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/113_7636feae-a48a-491b-8df3-017cb9603b28.jpg?v=1760666386', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/25000_06.jpg?v=1767344516', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/092_a40afaa7-951d-431e-bc2c-685d6a940dd1.jpg?v=1760666386', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_31e1d2c4-1c42-4087-9cf8-d105e148e02e.jpg?v=1760666386', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/143_8c4fc107-83c6-4d23-992e-efea0098a8cc.jpg?v=1760666386', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/25000_05.jpg?v=1760666386', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/151_103069e3-f057-4e1a-8370-e14a74c4704e.jpg?v=1767344516', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/7500_00_1.jpg?v=1767344516', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/5d89d90ba1230750fd5d1daf189d329d.jpg?v=1760666386', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/25000_02.jpg?v=1760666386', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/161.jpg?v=1767344516', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_b47b4628-9d07-42df-ae5f-592b6afdd788.png?v=1767344516', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b.png?v=1760666386', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/2_cb8df0ed-40cd-4e2b-89be-7d28dc5cffce.jpg?v=1760666386', 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/25000_00_d4e2f4d8-77b3-429e-b8e4-b35e9866958d.jpg?v=1767344516']}, {'upc': 'PMEKR60006R02', 'data': ['transfer'], 'size': 'MILD(2000)', 'price': 28.0, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1767344516', 'price_full': 35.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136519728', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-16 01:05:20'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1767344516', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-15 07:47:43'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1767344516', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-15 07:47:32'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1767344516', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-15 04:09:47'}, {'data': {'data': {'dataFacets': []}, 'name': 'Zero Exosome Shot', 'brand': 'Medicube', 'gender': 'Unisex', 'rating': 4.73, 'is_lost': 0, 'variants': [{'upc': 'KUSMEA1715', 'data': ['transfer'], 'size': 'BUNDLE(2000+7500)', 'price': 55.5, 'colors': ['Default'], 'image_url': 'https://cdn.shopify.com/s/files/1/0156/3905/2336/files/1_5_22dd25ad-b543-42bb-8bc1-8902e970447b_400x.png?v=1760666386', 'email_meta': '1760666386', 'price_full': 74.0, 'remote_url': 'https://medicube.us/products/exosome-shot?variant=41200136585264', 'description': 'Color: Default; 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You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\n \n\n Drawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\n \n\nNon-comedogenic\n\nTested to be Low-Irritating\n\nGluten-Free\n\nNo artificial color\n\nNet wt. 1.01 fl. oz. / 30ml\n\n STUDY RESULTS \n\nResults from a consumer use study\n\n100%\n\n Feels like receiving professional care, providing a pleasant sensation.\n \n\n Overall product satisfaction.\n\n Positive feedback from a 20-person survey, with individual variances.\n\n Tested by the Global Institute of Dermatological Science.\n\n Test period: August 24, 2022 - September 21, 2022.\n \n\nResults from a self test report\n\nAbsorption of active ingredients\n\n Absorption of active ingredients in cosmetics compared to standalone use\n +242% \n\nPore Care Effect\n \n\n Pore density care -21.1% \n\n Decrease in pore visibility -21.1%\n\n Pore area -15.3%\n\n Pore volume -16.7%\n\nOther skin enhancements\n\n Dead Skin Cells improvement +88.7% \n\n Enhancement of radiance +51.7%\n\n Sebum improvement +8.9%\n\n Surface hydration enhancement +7.6%\n\n Texture refinement +4.1%\n\n Skin barrier enhancement +54.2%\n\n Line volume care +10.4%\n\n Melanin pigmentation improvement +7.4%\n\n Freckles, blemishes visibility care +4.8%\n\n * Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\n FORMULATED WITHOUT \n\n Formulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n \n\n HOW TO USE\n\nBEGINNER\n\n If you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\n\n Step 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners). \n\n Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\n\n Step 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n \n\nSTANDARD\n\n Step 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine. \n\n Step 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\n\n Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\n\nPro tip! \n\n To maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\n \n\nUsage Notes : \n\n Avoid applying near the eyes and lips. \n\n For sensitive and delicate skin, we recommend conducting a patch test\n before use. \n\n To achieve optimal efficacy, please familiarize yourself with the\n instructions for use. \n\n You may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n \n\n FAQ \n\nQ. Is it normal for my face to tingle after application?\n\n Exosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\n \n\n This is a natural reaction as the active ingredients are being delivered\n to the pores. \n\n We recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\n \n\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\n\n This product is not meant to be rinsed off. \n\n Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\n \n\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\n\n The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\n \n\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\n\n The spicules are designed to naturally shed along with the dead skin over several days after application.\n\n Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\n \n\nQ. Are there any ingredients that should not be used together with\n it?\n\n There are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions. \n\n Please conduct a patch test and adjust the amount and frequency of use\n accordingly.\n \n\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\n\n When used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream. \n\n * Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.\n\nType: ZERO LINE - Pore Care\n\nTags: ALL, beauty, BESTSELLERS, PRODUCTS, treatments, zero\n\nOVERVIEW\nTingling Ampoule\nTingling sensation is natural. You may experience a tingling sensation,\n which may last for some time, but rest assured that this is a natural\n reaction to the Zero Exosome Shot.\nDrawing upon the principles of microneedling, we\'ve crafted a\n micro-sized, needle-shaped booster to target a range of skin issues.\n Enhanced with 15M patented Exosome shots, this formula physically\n delivers active ingredients to pores, providing daily intensive\n treatments for home use. Clinically validated to care for pore size,\n smooth skin texture, strengthen the skin barrier, and promote a radiant\n complexion.\nNon-comedogenic\nTested to be Low-Irritating\nGluten-Free\nNo artificial color\nNet wt. 1.01 fl. oz. / 30ml\n\nSTUDY RESULTS\nResults from a consumer use study\n100%\nFeels like receiving professional care, providing a pleasant sensation.\nOverall product satisfaction.\nPositive feedback from a 20-person survey, with individual variances.\nTested by the Global Institute of Dermatological Science.\nTest period: August 24, 2022 - September 21, 2022.\nResults from a self test report\nAbsorption of active ingredients\nAbsorption of active ingredients in cosmetics compared to standalone use\n +242%\nPore Care Effect\nPore density care -21.1%\nDecrease in pore visibility -21.1%\nPore area -15.3%\nPore volume -16.7%\nOther skin enhancements\nDead Skin Cells improvement +88.7%\nEnhancement of radiance +51.7%\nSebum improvement +8.9%\nSurface hydration enhancement +7.6%\nTexture refinement +4.1%\nSkin barrier enhancement +54.2%\nLine volume care +10.4%\nMelanin pigmentation improvement +7.4%\nFreckles, blemishes visibility care +4.8%\n* Excerpt from Medicube Exosome Shot Test Report and Survey, Results may\n vary.\n\nFORMULATED WITHOUT\nFormulated without 1,4 Dioxane, Acrylates, Alkylphenols (Octylphenols,\n nonylphenols) and Alkylphenol Ethoxylates, Aluminum powder, Aluminum\n Salts and complexes in antiperspirants, Animal Musk\'s/Fats/Oils,\n Benzophenones and related compounds, Benzyl Alcohol, Black 3,\n Butoxyethanol, Butylated hydroxyanisole (BHA), Butylated hydroxytoluene\n (BHT), Carbon Black or Black 2, Coal Tar, Cyclic Silicones, Dioxin, EDTA\n and derivatives, Ethanolamines, Ethoxylated Ingredients (including PEGS\n or polyethylene glycol), Ethylhexyl Ethylhexanoate, Formaldehyde and\n Formaldehyde-releasing agents, Fragrances, Heavy metals, Hydroquinone,\n Latex, Lead and Lead Acetate, Mercury and Mercury Compounds\n (Thimerisol), Methoxyethanol, Methyl Cellosolve, Methyl Cellosolve\n (Ethylene glycol monomethyl ether or 2-Methoxyethanol),\n Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MIT),\n Mineral Oil, Nanomaterials, Nitromusks and Polycyclic Musks, Octinoxate,\n Oxybenzone, Parabens, Perfluorinated compounds (PTFE, PFAS, PFOA, PFOS),\n Petrolatum and Paraffin, Phenoxyethanol, Phenylenediamine,\n phenylenediamine salts & phenylenediamine derivatives, Phthalates, PFAS\n compounds, Plastic Microbeads, Polyacrylamide and Acrylamide,\n Polyethylene microbeads, polypropylene microbeads & polystyrene\n microbeads (restricted in rinse-off products only), Resorcinol, Retinol\n and esters, Retinyl Palmitate, Styrene, Sulfates, Talc, Thimerosal,\n Toluene, Triclosan and Triclocarban, Undisclosed Synthetic Fragrance and\n more.\n\nHOW TO USE\nBEGINNER\nIf you are not familiar with skincare products containing spicules, we\n do not recommend using them with our AGE-R devices.\nStep 1. After cleansing, prepare your skin with Meicube\'s Zero Pore Pads\n (or other hydrating toners).\nStep 2. Apply the Zero One Day Exosome Shot to the desired area (e.g.,\n areas with uneven texture, enlarged pores, etc.) and gently rub and\n press to aid absorption.\nStep 3. Finish with Medicube\'s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nSTANDARD\nStep 1. After cleansing, apply the Zero One Day Exosome Shot to your\n entire face, avoiding the area near your eyes and lips. For the best\n results, we recommend using the Exosome Shot as the first step in your\n skincare routine.\nStep 2. Gently rub and press with your hands to ensure that the\n needle-like formula is absorbed deep into your skin.\nStep 3. Finish with Medicube’s Collagen Jelly Cream (or your daily\n water-based moisturizer).\nPro tip!\nTo maximize the effect, apply the Zero One Day Exosome Serum after using\n the "Air Shot Mode" of the AGE-R Booster Pro.\nUsage Notes :\nAvoid applying near the eyes and lips.\nFor sensitive and delicate skin, we recommend conducting a patch test\n before use.\nTo achieve optimal efficacy, please familiarize yourself with the\n instructions for use.\nYou may experience a tingling, redness, itching, and heat sensation which may last for some time,\n but rest assured that this is a natural reaction to the Exosome Shot.\n\nFAQ\nQ. Is it normal for my face to tingle after application?\nExosome Shot Ampoule contains naturally derived micro-particle\n ingredients, which may cause a tingling sensation upon application.\nThis is a natural reaction as the active ingredients are being delivered\n to the pores.\nWe recommend adjusting the amount and frequency of use based on\n individual skin sensitivity.\nQ. Do I simply wash it off or do I maintain my regular skincare routine afterwards?\nThis product is not meant to be rinsed off.\nInstead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.\nQ. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot?\nExosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA).\nThe Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system.\nQ. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?\nThe spicules are designed to naturally shed along with the dead skin over several days after application.\nAny residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.\nQ. Are there any ingredients that should not be used together with\n it?\nThere are no specific ingredients that should not be used together;\n however, individuals with sensitivity should be cautious as certain\n ingredients may cause irritation or hypersensitivity reactions.\nPlease conduct a patch test and adjust the amount and frequency of use\n accordingly.\nQ. I want to focus on managing my pores. Are there any synergistic\n products that work well together?\nWhen used in conjunction with the Exosome Shot, the One-day Serum and\n One-day Cream result in an 88% improvement in pore volume and an 85%\n improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot\n Ampoule first, followed by the One-day Serum, and finishing with the\n One-day Cream.\n* Excerpts from in vivo absorption tests for improving skin absorption\n depth compared to using One-day Serum + One-day Cream alone. /\n Individual results may vary.', 'remote_code': 'exosome-shot', 'rating_count': 407, 'partial_update': 0, 'product_images': []}, 'date': '2026-07-15 01:06:37'}] |